Endocrine Disruptors: Effects on Male and Female Reproductive Systems by Rajesh K. Naz (Editor) Purchase at:  Amazon.com  Format: Hardcover, 358pp.  ISBN: 0849331641 Publisher: CRC Press, LLC  Pub. Date: January 1999

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Book Description

An examination of the hazards environmental toxicants pose to reproductive function. Endocrine Disruptors: Effects on Male and Female Reproductive Systems examines the epidemiology and etiology of environmental toxicants/hormone imposters, many of which act as reproductive toxicants that cause fertility problems and carcinogenic hazards. Thus far, over fifty such hormone imposters/persistent organic pollutants (POPs) have been identified, the most common of which are organochlorines (DDT, PCBs) and dioxins. This book discusses the hazardous effects of endocrine disruptors on gonads, fertility, and sexual and reproductive function, and health hazards leading to the alarming decline in global fertility and rising incidences of breast and prostate cancer.

Card catalog description

Endocrine Disruptors: Effects on Male and Female Reproductive Systems examines the epidemiology and etiology of environmental toxicants, or "hormone imposters," many of which act as reproductive toxicants that cause fertility problems. This book addresses alarming issues such as declining global fertility; rising incidences of breast and prostate cancer; and the wide variety of toxic effects that the synthetic chemicals, termed endocrine disruptors, exert on the gonads, fertility, and sexual and reproductive function.

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From Booknews

Examines the epidemiology and etiology of environmental toxicants, also known as hormone impostors, many of which act as reproductive toxicants that cause fertility problems. The 12 contributions address issues such as declining global fertility, rising incidences of breast and prostate cancer, and the wide variety of toxic affects that the synthetic chemicals exert on the gonads, fertility, and sexual and reproductive function. Individual topics include: how diethylstilbestrol and environmental estrogens influence the developing female reproductive system; dietary phytoestrogens; endocrine disrupters and male infertility; and the role of natural and man made estrogens in prostate development. Annotation c. by Book News, Inc., Portland, Or.

Table of Contents

Sect. I Effect on the Female Reproductive System

1 Nontraditional Sites of Endocrine Disruption by Chemicals on the Hypothalamus-Pituitary-Gonadal Axis: Interactions with Steroid Membrane Receptors, Monoaminergic Pathways, and Signal Transduction Systems   3

2 Diethylstilbestrol (DES) and Environmental Estrogens Influence the Developing Female Reproductive System   39

3 Ovotoxic Environmental Chemicals: Indirect Endocrine Disruptors   57

4 Dietary Phytoestrogens   89

5 Estrogens, Xenoestrogens, and the Development of Neoplasms   125

6 Differential Regulation of Gene Expression by Estrogenic Ligands: A Potential Basis for the Toxicity of Environmental Estrogens   165

7 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Related Environmental Antiestrogens: Characterization and Mechanism of Action   187

Sect. II Effect on the Male Reproductive System

8 Endocrine Disruptors and Male Infertility   225

9 Environmental Antiandrogens as Endocrine Disruptors   247

10 Endocrine Disruptors and Sexual Dysfunction   279

11 The Role of Natural and Manmade Estrogens in Prostate Development   307

12 Metal Ions and Prostate Cancer   329

Index   339