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Description from Amazon.comBook DescriptionFive million Americans want children but cannot conceive. One million couples seek infertility treatment every year, almost always without prior knowledge of the physical, emotional, and financial costs of high-tech conception (as a rule it is not covered by insurance), and without any way to judge the hard-sell come-ons of what is now a $2-billion, for-profit, unregulated industry that preys on their desperate hopes by promising outcomes that are all too rarely successful. This authoritative, lucid, balanced, and forthright book describes the very latest information on high-tech conception, with information on techniques of fertilization, the latest research, and the nature and risks of the potent drugs used to assist in fertilization and implantation. Its goal is to help infertile individuals become informed consumers by describing the different procedures, and showing them how to interpret and compare clinics' claimed success rates; examine the factors that affect success; critically assess the safety of the different techniques both for the mothers and the babies born through such procedures; and understand the importance of genetic screening in in vitro fertilization. Back CoverIf you are among the millions of Americans who want children but have been unable to conceive, this book is for you. If none of the low-tech approaches have worked and you are considering in-vitro fertilization or one of the newer techniques, this is the book you need before beginning your quest for treatment. Providing lucid, balanced, forthright, and thorough information about high-tech conception, it includes guidelines for choosing the right approach for your type of infertility, help in making a realistic appraisal of your chance of success, critical assessments of both the benefits and risks of the newer technologies, detailed step-by-step explanations of the procedures themselves, full-scale profiles of the highly potent drugs used to stimulate ovulation, groundbreaking information on the critically important process of preimplantation genetic diagnosis, and much more. Description from BarnesandNoble.comAnnotation"...discusses techniques appropriate for each type of fertility, step-by-step procedures, the nature & risks of drugs used, the process of prenatal genetic diagnosis, & how to assess the safety & claimed success rates of clinics" From the PublisherFive million Americans want children but cannot conceive. One million couples seek infertility treatment every year, almost always without prior knowledge of the physical, emotional, and financial costs of high-tech conception (as a rule it is not covered by insurance), and without any way to judge the hard-sell come-ons of what is now a $2-billion, for-profit, unregulated industry that preys on their desperate hopes by promising outcomes that are all too rarely successful. This authoritative, lucid, balanced, and forthright book describes the very latest information on high-tech conception, with information on techniques of fertilization, the latest research, and the nature and risks of the potent drugs used to assist in fertilization and implantation. Its goal is to help infertile individuals become informed consumers by describing the different procedures, and showing them how to interpret and compare clinics' claimed success rates; examine the factors that affect success; critically assess the safety of the different techniques both for the mothers and the babies born through such procedures; and understand the importance of genetic screening in in vitro fertilization. Table of ContentsPreface Introduction I Reproduction and Infertility 1 1 Normal Reproduction 3 2 Infertility and Reproductive Disorders 10 3 Diagnosing Infertility 16 II Issues in High-Tech Conception 19 4 Deciding When High-Tech Conception Is Appropriate 21 5 Interpreting and Comparing Success Rates 30 6 Choosing a Clinic 46 7 Evaluating the Quality of Fertility Information 57 III Techniques Used in High-Tech Conception 71 8 Ovulation Induction 73 9 In Vitro Fertilization (IVF) 90 10 Tubal Transfer Techniques 101
11 Treatments for Male-Factor Infertility 112
12 Luteal Phase Support 136 13 Assisted Hatching 140 14 Co-culture of Embryos 143 15 Cryopreservation 147 16 Oocyte Donation/Donor Egg IVF 157 17 Immunotherapy 164 18 Immature Oocyte Retrieval/Maturation 178 19 Multifetal Pregnancy Reduction 181 IV Drugs Used in High-Tech Conception 187 20 Aspirin 191 21 Bromocriptine 195 22 Chorionic Gonadotropin (hCG) 200 23 Clomiphene 204 24 Danazol 209 25 Doxycycline 212 26 Follitropin (rFSH) 215 27 Gonadorelin (GnRH) 220 28 Heparin 223 29 Immune Globulin (IVIg) 227 30 Leuprolide 231 31 Menotropins (hMG) 235 32 Methotrexate 242 33 Nafarelin 246 34 Progesterone 250 35 Urofollitropin (FSH) 253 V The Safety of High-Tech Conception 259 36 Risks of Ovulation Drugs 264 37 Risks of Surgical Procedures in Assisted Reproduction 274 38 Risks of High-Tech Pregnancies 276 39 Risks of Genetic Defects in IVF Children 286 VI Preimplantation Genetic Diagnosis 291 40 Genetics Review 294 41 Genetic Diseases 299 42 Prenatal Genetic Testing 305 43 Current Use of Preimplantation Genetic Diagnosis 308 44 Preconception Diagnosis 315 Resources 319 Notes 323 Glossary 327 Index 349
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